This seminar will provide an updated review of clinically relevant recent advances in neurobiology with a focus on the pathophysiology and psychopharmacological treatment of the major psychiatric disorders. The seminar will focus on the treatment of schizophrenia, bipolar disorder, depression, and anxiety spectrum disorders. The effectiveness of atypical and conventional antipsychotic drugs, as well as newer medications, will be reviewed. The seminar will address strategies for bipolar patients who are noncompliant or treatment-resistant, approaches to the acutely psychotic, recovering psychotic patient, and the concept of early intervention. Special consideration will be given to ketamine, ECT, TMS and augmentation strategies in treatment-resistant depression,

The role of switch versus augmentation and combination strategies for treatment-resistant depression will be reviewed as well as best treatments for subtypes of major depression including atypical depression. The role of psychopharmacology in the treatment of generalized anxiety disorders, OCD, panic, and traumatic syndromes will be highlighted. The latest advances in child and adolescent psychopharmacology will be presented. Throughout the seminar, the establishment and importance of the therapeutic alliance when prescribing all psychotropic medications will be underscored, as will the potential hazards/benefits of polypharmacy drug interactions.

FACULTY
Alan I. Green, MD, Russell G. Vasile, MD, Roscoe O. Brady Jr. MD, PhD,
Barbara J. Coffey, MD, MS. See bios on website.